<![CDATA[sibapharm.com - Blog]]>Fri, 07 May 2021 13:37:33 -0500Weebly<![CDATA[Types of Iron Supplements]]>Sat, 23 Jan 2021 00:53:02 GMThttp://sibapharm.com/blog/types-of-iron-supplements
Oral iron : There are different types of elemental iron that have different absorption. Most of these agents have side effects including constipation and GI upset that make them less tolerable by patients and most patients stop or even reduce recommended doses to try to reduce side effects. On the other hand, absorption of most of the elemental iron commercial available by the gut is altered by the food that we eat making their absorption very erratic and unreliable. 

Intravenous Iron : Iron in the intravenous form, though ensures availability of iron in body and does not depend on the guts absorption, it is however very expensive. It is also known to cause severe allergic reactions in few patients. 

Liposomal Iron : It is a form of iron that is in the oral form that is as good as Intravenous iron, research as shown. Thus liposomal iron is currently the most superior type of iron. 

Basically, iron is transported through a liposome that is like a car that ensures that iron reaches to the intestines where the absorption of iron happens safely.    It is thus not altered by any food or by acidity in the stomach. Moreover, it doesn't have the typical side effects of elemental iron like constipation or GI upset that makes it  much more tolerated by patients with faster absorption and repletion of iron stores. 
<![CDATA[Iron Deficiency Facts you did not know about !]]>Sat, 23 Jan 2021 00:41:23 GMThttp://sibapharm.com/blog/iron-deficiency-facts-you-did-not-know-about
  • More than one-fourth of the world's population 
  • One half of patients with anemia are preschool children and women.
  • 2% of Adults suffer from Iron deficiency anemia
  • 12-17% of Adults above the age of 65 years have iron deficiency
<![CDATA[Causes of Iron Deficiency Anemia]]>Sat, 23 Jan 2021 00:38:32 GMThttp://sibapharm.com/blog/causes-of-iron-deficiency-anemiaAnemia of inflammation: hepcidin-induced block in the release of iron from the macrophage back into the circulation, making iron less available. Commonly seen in patients with infection, inflammation, or malignancy.
Treatment with erythropoiesis-stimulating agents: In normal subjects, chronic renal disease or malignancy, available body iron supplies may be unable to release iron rapidly enough to satisfy the increase in erythropoiesis brought about by the use of erythropoiesis-stimulating agents
<![CDATA[Too much side effects of Iron therapy...]]>Wed, 16 Dec 2020 06:00:00 GMThttp://sibapharm.com/blog/too-much-side-effects-of-iron-therapy
Iron supplementation is associated with alot of side effects. Our Ferrosom has the least chance to have side effects in comparison to other formulations on the market. 

If you choose to take other formulations of iron, you made decrease the side effects by doing the following:
  • Reducing your daily dose of iron.
  • Taking iron with food or milk (though this may reduce absorption).
  • Switching to a formulation with a lower amount of elemental iron.
  • Using liquid formulation instead of tablets.
<![CDATA[How does Ferrosom work?]]>Tue, 08 Sep 2020 05:00:00 GMThttp://sibapharm.com/blog/how-does-ferrosom-work
Liposomes are bilayer (double-layer), liquid-filled bubbles made from lipid layer. Researchers discovered that these spheres could be filled  with nutrients and used to protect and deliver these agents into the body and even into specific cells of the body.

The bilayer structure of liposomes is nearly identical to the bilayer construction of the cell membranes that surround each of the cells in the human body. This occurs because of the unique composition of phospholipids. The phosphate (source of "phospho" in phospholipid) head of phospholipids is hydrophilic — it loves water — whereas the fatty-acid tails (lipids) are hydrophobic — they hate water.

When phospholipids find themselves in a water-based solution, the hydrophobic tails quickly move to distance themselves from the liquid just like oil separates from vinegar. So, as all the tails turn inward and all the heads turn toward the liquid, they form a double-layered membrane.

Theories for how does the Liposomes deliver the nutrition to the cells:
1- One theory suggests that the phospholipids are processed in the liver as fats and that this process releases the nutrient. 
2- Another theory proposes that cells all over the body, hungry for phospholipid materials to repair cell membranes and other cellular structures, "steal" these materials from the liposome allowing their contents to leak out.

Quite possibly both processes occur. In any case, the therapeutic value and greatly increased delivery of liposome-encapsulated drugs and nutrients has been scientifically confirmed countless times. At present, liposome's are the most bioavailable oral way to deliver nutrients.